Methyl derivatives of folic acid as intermediates in the methylation of homocysteine by Escherichia coli.
نویسندگان
چکیده
Epstein, S. S. & Weiss, J. B. (1960). Biochem. J. 75, 247. Foster, M. A., Jones, K. M. & Woods, D. D. (1961a). Biochem. J. 80, 519. Foster, M. A., Rowbury, R. J. & Woods, D. D. (1963). J. gen. Microbiol. 31, xix. Foster, M. A., Tejerina, G. & Woods, D. D. (1961 b). Biochem. J. 81, 1P. Gibson, F. & Woods, D. D. (1960). Biochem. J. 74. 160. Gorini, L. & Maas, W. K. (1958). In The Chemical Basis of Development, p. 469. Ed. by McElroy, W. D. & Glass, B. Baltimore: The John Hopkins Press. Guest, J. R. (1960). Biochem. J. 76, 405. Guest, J. R., Foster, M. A. & Woods, D. D. (1964a). Biochem. J. 92, 488. Guest, J. R., Friedman, S., Foster, M. A., Tejerina, G. & Woods, D. D. (1964b). Biochem. J. 92, 497. Guest, J. R., Helleiner, C. W., Cross, M. J. & Woods, D. D. (1960). Biochem. J. 76, 396. Guest, J. R. & Woods, D. D. (1960). Biochem. J. 77, 422. Guest, J. R. & Woods, D. D. (1962a). 2 Europdisches Sympo8ion uber Vitamin B12 und Intrinsic Factor, p. 686. Ed. by Heinrich, H. C. Stuttgart: Ferdinand Enke Verlag. Guest, J. R. & Woods, D. D. (1962b). Biochem. J. 82, 26. Hatch, F. T., Cathou, R. E. & Larrabee, A. R. (1960). Fed. Proc. 19, 417. Hatch, F. T., Larrabee, A. R., Cathou, R. E. & Buchanan, J. M. (1961). J. biol. Chem. 236, 1095. Hatch, F. T., Takeyama, S. & Buchanan, J. M. (1959). Fed. Proc. 18, 243. Jones, K. M., Guest, J. R. & Woods, D. D. (1961). Biochem. J. 79, 566. Kisliuk, R. L. (1960). Biochim. biophys.Acta, 40, 531. Kisliuk, R. L. (1961). J. biol. Chem. 236, 817. Kisliuk, R. L. & Woods, D. D. (1960). Biochem. J. 75, 467. Larrabee, A. R. & Buchanan, J. M. (1961). Fed. Proc. 20, 9. Layne, E. (1957). In Methods in Enzymology, vol. 3, p. 451. Ed. by Colowick, S. P. & Kaplan, N. 0. New York: Academic Press Inc. Nakao, A. & Greenberg, D. M. (1958). J. biol. Chem. 230, 603. Stevens, A. & Sakami, W. (1959). J. biol. Chem. 234, 2063. Szulmajster, J. & Woods, D. D. (1960). Biochem. J. 75, 3. Takeyama, S. & Buchanan, J. M. (1960). Fed. Proc. 19, 417. Wilmanns, W., Rucker, B. & Jaenicke, L. (1960). HoppeSeyl. Z. 322, 283.
منابع مشابه
Folic acid and the methylation of homocysteine by Bacillus subtilis.
1. Cell-free extracts of Bacillus subtilis synthesize methionine from serine and homocysteine without added folate. The endogenous folate may be replaced by tetrahydropteroyltriglutamate or an extract of heated Escherichia coli for the overall C(1) transfer, but tetrahydropteroylmonoglutamate is relatively inactive. 2. Extracts of B. subtilis contain serine transhydroxymethylase and 5,10-methyl...
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ورودعنوان ژورنال:
- The Biochemical journal
دوره 92 3 شماره
صفحات -
تاریخ انتشار 1964